Pluripotent and Early Differentiation Antibodies

Pluripotent and Early Differentiation

Embryonic stem cells derive from the inner cell mass of the blastocyst. They differentiate into three primary germ layers: ectoderm, endoderm, and mesoderm, giving rise to virtually all the cells of the body except the placenta.

Takahashi and Yamanaka found the process is reversible under certain conditions and a terminally differentiated cell can be reprogrammed into a pluripotent stem cell.

AbD Serotec offers a broad collection of antibodies useful for studying pluripotent stem cells and those in the early stages of differentiation. Click on the links below to explore our product range.

CD24

CD9

nanog

smad

Runx2

myc

CD30

GSC

oct-4

Sox2


References
  1. Takahashi K. and Yamanaka S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
    Cell 126(4):663-76
  2. International Stem Cell Initiative, various authors (2007) Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
    Nat Biotechnol 25(7):803-16