HuCAL® Anti-drug Antibodies

Fully human reference Igs for immune response (IR) assays

The Human Combinatorial Antibody Library (HuCAL) supports therapeutic drug development efficiently with highly specific, monoclonal, anti-drug antibodies (ADAs). Try our fully-defined, reliable, custom human antibody standards to save assay development resources.

• Truly human recombinant immunoglobulin reference standards
• Ready for delivery in earliest pre-clinical stages: independent of patient or primate sources, or mouse-derived, chimeric anti-drug antibodies
• Convertible into various isotypes: IgA, IgE, IgG, or IgM
• Excellent specificity for the drug under development
• Our single antibody solution for both IR and pharmacokinetic (PK) assays
• An unlimited, guaranteed supply eliminates the need for revalidation of new sources in extensive clinical studies

The highly specific HuCAL ADAs are developed solely in vitro, pre-adsorbed against any available controls and human serum. An option to screen for inhibiting/neutralizing antibodies is also offered.

To view a schematic of the HuCAL ADA generation process, when used to create anti-idiotypic antibodies, click here.

AbD Serotec has a range of  ready made Anti-idiotypic Antibodies, click here.

HuCAL ADA projects benefit from our success rate of over 90% and our No Antibody – No HuCAL Library Screening Charge Guarantee