Why Choose HuCAL®?

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HuCAL technology is fast and flexible, and with a wide range of benefits over traditional antibody development techniques using hybridomas it is the optimal choice for your next custom monoclonal antibody generation project. AbD Serotec offers Fab antibody generations in as little as 8 weeks, a success rate of over 90%, and the following guarantees:

Our Guarantees

  • No Antibody-No HuCAL Library Screening Charge

AbD Serotec is absolutely confident that at least one of our 45 billion HuCAL antibody specificities is the perfect match for your antigen. If we do not deliver at least one ELISA-positive antibody, then there will be no charge for the HuCAL library screening in a standard HuCAL project.

  • Animal-Free Technology

Selection, screening, and expression of HuCAL antibodies is performed in vitro and does not require the use of animals.

HuCAL Antibody Technology

Guided Selection Fully in vitro processes allow AbD Serotec to direct specificities toward chosen epitopes and to use a broad range of buffer conditions and antigens
Rapid Production High levels of automation and flexible in vitro methods lead to delivery of HuCAL Fab antibodies in as little as 8 weeks
Animal-Free All HuCAL processes occur in vitro and can include large-scale production under conditions free from animal-derived components
Secure Supply A secure supply of HuCAL antibodies is achieved with the doubly backed up storage system including storage of the DNA sequence of the antibody electronically as well as the DNA plasmid encoding the antibody genes physically 
Flexible Antibody Formats AbD Serotec offers monovalent and bivalent Fab antibodies with a choice of epitope tags, plus further conversion of Fab antibodies into full-length human and chimeric immunoglobulins 
Engineering and Optimization Since the HuCAL library is modular and composed of known DNA sequences, the antibodies can be rapidly optimized for affinity 
Fully Human Antibodies The HuCAL library was constructed de novo using human antibody gene sequences and as a result all HuCAL antibodies are fully human (not humanized)

Learn More about HuCAL

HuCAL Antibody Technology

Flexible Antibody Formats

Guided Selection Strategies

Success Stories

Project Solutions and Services

Ordering Information