Scientific Poster Download

Fast Development of Highly Specific Fully Human Anti-Idiotypic Antibodies

Härtle S., et al (2009) Abstracts of IBC’s 7th Annual International Conference on Antibody Therapeutics: 2009 December 8-10, San Diego, California.

This poster illustrates the suitability of HuCAL® Custom Monoclonals for PK and ADA Assays. In addition to the immune response (IR) assay data, this poster also includes:

• Details of the HuCAL anti-idiotype (anti-ID) antibody generation process
• Inhibition of binding of target antibody
• Specificity testing
• Direct PK assay: anti-ID antibody as detection reagent
• IR assay: anti-ID antibody mimicking anti-drug antibody response

Further information about HuCAL anti-drug antibodies is available here