IgM antibody | M15/8
Mouse anti Human IgM
- Product Type
- Monoclonal Antibody
- Clone
- M15/8
- Isotype
- IgG1
- Specificity
- IgM
Mouse anti Human IgM monoclonal antibody, clone M15/8 recognizes human IgM, binding to the μ heavy chain. The antibody does not cross-react with other immunoglobulin classes. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- TRIS buffered saline.
- Preservative Stabilisers
- <0.1% sodium azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 5ug/ml as coating Ab | ||
Flow Cytometry | 20ug/ml | ||
Immunohistology - Frozen | 20ug/ml | ||
Immunoprecipitation |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse IgG1 Negative Control | MCA928 | F | 100 Tests | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Mouse IgG1 Negative Control |
References for IgM antibody
-
Cragg, M.S. et al. (1999) Analysis of the interaction of monoclonal antibodies with surface IgM on neoplastic B-cells.
Br J Cancer. 79 (5-6): 850-7. -
Irie, E. et al. (2010) Severe hypogammaglobulinemia persisting for 6 years after treatment with rituximab combined chemotherapy due to arrest of B lymphocyte differentiation together with alteration of T lymphocyte homeostasis.
Int J Hematol. 91: 501-8. -
Creasey, A.M. et al. (2003) Nonspecific immunoglobulin M binding and chondroitin sulfate A binding are linked phenotypes of Plasmodium falciparum isolates implicated in malaria during pregnancy.
Infect Immun. 71: 4767-71. -
Ghumra, A. et al. (2012) Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasites.
PLoS Pathog. 8 (4): e1002665. -
Semblat, J.P. et al. (2015) Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain.
Mol Biochem Parasitol. 201 (1): 76-82.
- RRID
- AB_321861
- UniProt
- P01871
- Entrez Gene
- IGHM
- GO Terms
- GO:0003823 antigen binding
- GO:0016021 integral to membrane
- GO:0005624 membrane fraction
MCA1662
156303 163405 170308If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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