Acute-phase proteins are primarily produced in the liver under the control of cytokines and include proteinase inhibitors (alpha 1 antitrypsin, alpha 1 antichymotryspin), coagulation factors (fibrinogen, prothrombin, factor VIII plasminogen), complement (C1s, C2, B, C3, C4, C5, C1 inhibitor) and transport proteins (haptoglobin, ceruloplasmin). Other acute phase proteins of interest are serum amyloid A protein (SAA), fibronectin and alpha 1 acid glycoprotein.
AbD Serotec offers a number of reliable antibodies to human serum proteins. All these antibodies are available in bulk quantities, and because they are supported by unrivaled technical support and our ISO quality system, they are ideal for immunodiagnostic kit development. We sell polyclonal antisera ideal for turbidimetric & nephelometric assays which can be purified to customers’ specifications.