Custom Polyclonal Antibody Production Service

AbD Serotec offers a range of custom polyclonal antibody production services to provide the most cost-effective option for Client projects.

• Bulk quantity polyclonal antibody production projects
• Goat, rabbit and sheep hosts - other species available on request
• Customized and flexible projects to meet your requirements
• Modification specific polyclonal antibodies e.g. phospho-specific
• ISO 9001:2000 and ISO 13485:2003 quality systems

When you need your own novel antibody generated for a special project, our custom polyclonal antibody production service will deliver. From concept to completion our reliable custom polyclonal antibody production service provides you with utmost discretion and unrivalled technical support to manage your project. A signed Confidential Disclosure Agreement is available on request.

Antibody Production

You provide the protein antigen or peptide sequence and we’ll produce the polyclonal antibody for you, saving you time and resources! Our custom polyclonal antibody production service can be tailored to meet your specific project requirements including peptide synthesis, carrier protein conjugation, ELISA QC screening, and serum purification. We also offer you the flexibility of extending your project on a monthly basis, particularly suitable for custom polyclonal antibody production in larger animal hosts.

We provide polyclonal antibody production in the popular host species below – please inquire for polyclonal antibody development in other species.

Project inclusive of

• Cost of animals plus housing for the term of the project
• Pre-immune bleeds if requested
• 3 - 4 immunizations per animal
• Test bleeds if requested
• Collection of production bleeds after the final immunizations

Serum Purification

Protein A, Protein G, ammonium sulfate and peptide affinity purification (free N-terminus or terminal cysteine) are offered for purification of the immunoglobulin. Typical yield from 25 ml of affinity purified sera using protein G chromatography is 2-3 mg/ml purified antibody.

Antibody Conjugation

We offer a variety of markers for antibody conjugation including: Alkaline Phosphatase, APC, Biotin, Dylight™ 405, Dylight™ 488, Dylight™ 549, Dylight™ 649, Dylight™ 800, FITC, HRP, and RPE. 

F(ab’)2 Fragments

For over 100 mg quantities of purified IgG we can produce F(ab’)₂ fragments from your polyclonal antibody.

Contact us for an initial confidential consultation to discuss your specific custom polyclonal antibody production project requirements.

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