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- Viral CYTOMEGALOVIRUS
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Product CodePIP005
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DescriptionNATIVE CYTOMEGALOVIRUS
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Product TypeAntigen
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FormatInactivated Pathogen
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ApplicationsE
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Pack Size1 ml
Product Summary
Additional Formats
Related Reagents
More Images
Application Notes
References
More Information
Viral CYTOMEGALOVIRUS Product Summary
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Specificity
Cytomegalovirus is a member of the Herpesviridae family. It may be transmitted from person to person through urine, saliva, other bodily fluids, breast milk and transplanted organs. It is a common infection which mostly passes unnoticed. The infection may be dangerous to people who are immunocompromised such as those who are HIV positive or organ transplant recipients. The infection may also be dangerous to pre- and post-natal infants. Antiviral drugs are useful in the treatment of CMV infection.
Target Species
Viral
Product Form
Inactivated Cytomegalovirus - liquid
Preparation
MRC-5 monolayers are infected in a manner which will ensure that the full host of viral proteins are present upon harvest. Optimally infected tissue is collected in glycine buffered saline. The cells are disrupted to release cellular CMV antigen. Cellular debris is removed by centrifugation.
The antigen preparation is inactivated using gamma radiation, which primarily damages viral genetic material.
Preservative Stabilisers
None present
Activity
This product has been rendered inactive by standard procedures. However this material should still be handled as infectious and should be disposed of appropriately.
Approx. Protein Concentrations
Total protein concentration 3.3 mg/ml
Buffer Solution
Glycine buffered saline
Source
Cytomegalovirus strain AD-169, cultured in MRC-5, a diploid cell line of human lung origin.
Viral CYTOMEGALOVIRUS Additional Formats
Viral CYTOMEGALOVIRUS Related Reagents
Viral CYTOMEGALOVIRUS More Images
Viral CYTOMEGALOVIRUS Application Notes
Viral CYTOMEGALOVIRUS References
Viral CYTOMEGALOVIRUS More Information
Storage
Store at -70oC.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
Shelf Life
18 months from date of despatch.
Instructions For Use
PIP005 should be sonicated immediately before use to ensure the preparation is uniform. The product may be used in a variety of immunoassay formats or may be further purified to meet the requirements of a particular assay format.
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University of California San Fran-Mission Bay, CA February 29, 2012
Oregon Health & Science University Portland, OR March 14, 2012
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