Beta Amyloid antibody
Rabbit anti Human Beta Amyloid (aa1-42)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Beta Amyloid
- Region
- (aa1-42)
Rabbit anti Human beta amyloid antibody recognizes the beta amyloid (1-42) peptide, the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis, a muscle disease (Benveniste et al. 2015). Beta amyloid also forms aggregates coating cerebral blood vessels in cerebral amyloid angiopathy (Kirshner et al. 2015). Rabbit anti Human beta amyloid antibody (AHP677) may be used in immunohistochemical staining of Alzheimer's disease plaques. |
- Target Species
- Human
- Product Form
- Serum - liquid
- Antiserum Preparation
- Antisera to Beta amyloid (1-42) were raised by repeated immunisations of rabbits with highly purified antigen.
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Immunohistology - Frozen | |||
Immunohistology - Paraffin 1 | |||
Western Blotting | 1/500 | 1/1000 |
- 1This product requires formic acid pre-treatment of paraffin sections.
- Histology Positive Control Tissue
- Alzheimer's disease brain
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---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml | Log in | |||
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Description | Sheep anti Rabbit IgG:RPE |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB * | 0.5 ml | Log in | |||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
References for Beta Amyloid antibody
-
Bertrand, E. et al (2008) Amyloid angiopathy in idiopathic Parkinson's disease. Immunohistochemical and ultrastructural study.
Folia Neuropathologica. 46: 255-269. -
Carty, N.C. et al. (2006) Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice.
J Neuroinflammation. 3: 11. -
Jeffrey, M. et al. (2015) Membrane pathology and microglial activation of mice expressing membrane anchored or membrane released forms of Aβ and mutated human Alzheimer's precursor protein (APP).
Neuropathol Appl Neurobiol. 41 (4): 458-70. -
Jeffrey M et al. (2015) A Naturally Occurring Bovine Tauopathy Is Geographically Widespread in the UK.
PLoS One. 10 (6): e0129499. -
Ingwersen, J. et al. (2018) Nimodipine confers clinical improvement in two models of experimental autoimmune encephalomyelitis.
J Neurochem. Feb 23 [Epub ahead of print].
- RRID
- AB_2242734
- UniProt
- P05067
- Entrez Gene
- APP
AHP677
150260 159268If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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